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A liquid dose in millilitres

Reduce the stock to milligrams in one millilitre, then divide the milligrams wanted by that.

Hone is a place to practise a career, one idea a day. This is one of its lessons, written out in full and free to read without an account.

What it is for

Oral liquids are labelled as so many milligrams in so many millilitres, and the syringe in the bag is marked only in millilitres. Somebody has to turn one into the other, and it is you.

How to think about it

Two steps, always in the same order. First, milligrams per millilitre: the strength divided by the volume it is stated in. Second, the dose: milligrams wanted divided by milligrams per millilitre. Then check the size before you write it down.

Worked example

Stock: 250 mg / 5 mL
Two hundred and fifty milligrams in every five millilitres.
250 mg / 5 mL = 50 mg per mL
Reduce it to one millilitre first. Everything after this is easier.
Order 400 mg: 400 / 50 = 8 mL
Milligrams wanted over milligrams per millilitre.
400 mg is more than 250 mg, so the answer had to be more than 5 mL
And 8 mL is. That is the size check.

Your turn

The stock is 100 mg/mL and the order is for 350 mg. Write the volume of one dose.

350 / 100 =  mL

The trap

Using the 5 mL from the label as if it were the dose. It is the volume the strength is quoted over, not the amount anybody takes.

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